Structure of PDB 5grg Chain A

Receptor sequence
>5grgA (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYG
CDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HAAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRW
3D structure
PDB5grg Dual non-contiguous peptide occupancy of HLA class I evoke antiviral human CD8 T cell response and form neo-epitopes with self-antigens
ChainA
Resolution1.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 E63 N66 Y99 Q155 Y159 R163 W167 Y171 Y7 E63 N66 Y99 Q155 Y159 R163 W167 Y171
BS02 peptide A D77 Y84 D116 T143 K146 W147 D77 Y84 D116 T143 K146 W147
External links
PDB RCSB:5grg, PDBe:5grg, PDBj:5grg
PDBsum5grg
PubMed28698575
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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