Structure of PDB 5gp7 Chain A

Receptor sequence
>5gp7A (length=163) Species: 9606 (Homo sapiens) [Search protein sequence]
GPGSDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLA
AGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNT
CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLAT
ADDIRALLIDAMP
3D structure
PDB5gp7 USP25 regulates Wnt signaling by controlling the stability of tankyrases
ChainA
Resolution1.502 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.-
2.4.2.30: NAD(+) ADP-ribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R836 S838 L843 G846 Y847 L871 N876 Y880 H882 D900 W902 F904 E909 R42 S44 L49 G52 Y53 L77 N82 Y86 H88 D106 W108 F110 E115
External links
PDB RCSB:5gp7, PDBe:5gp7, PDBj:5gp7
PDBsum5gp7
PubMed28619731
UniProtO95271|TNKS1_HUMAN Poly [ADP-ribose] polymerase tankyrase-1 (Gene Name=TNKS)

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