Structure of PDB 5gm2 Chain A

Receptor sequence
>5gm2A (length=281) Species: 68180 (Streptomyces blastmyceticus) [Search protein sequence]
QQVTADEVGDWYDKFGEVYHLTLGESVHCGLWFPPDAPVPQDMELVTMSS
QAQDRYTDYLIETLDPKAGQHLLDIGCGTGRTALKAARQRGIAVTGVAVS
KEQIAAANRLAAGHGLTERLTFEVADAMRLPYEDESFDCAWAIESLCHMD
RAKALGEAWRVLKPGGDLLVLESVVTEELTEPETALFETLYAANVPPRLG
EFFDIVSGAGFHTLSLKDLSANLAMTMNVFALGVYSRRAEFTERFGAEFV
DGLLAGLGSAQETLIRKTRFFMATLRKPAVL
3D structure
PDB5gm2 Crystal structure and enantioselectivity of terpene cyclization in SAM-dependent methyltransferase TleD
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A G85 C86 G87 A107 V108 Q112 D135 A136 S154 H157 M158 G76 C77 G78 A98 V99 Q103 D126 A127 S145 H148 M149
BS02 TEX A E153 C156 E181 S182 F196 Y200 L232 M236 E144 C147 E172 S173 F187 Y191 L223 M227
BS03 SAH A V17 V36 H37 V8 V27 H28
BS04 TEX A Y28 L32 V36 H37 Y19 L23 V27 H28
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:5gm2, PDBe:5gm2, PDBj:5gm2
PDBsum5gm2
PubMed27613858
UniProtA0A077K7L1

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