Structure of PDB 5gm1 Chain A

Receptor sequence
>5gm1A (length=281) Species: 68180 (Streptomyces blastmyceticus) [Search protein sequence]
QQQVTADEVGDWYDKFGEVYHLTLGESVHCGLWFPPDAPVPQDMELVTMS
SQAQDRYTDYLIETLDPKAGQHLLDIGCGTGRTALKAARQRGIAVTGVAV
SKEQIAAANRLAAGHGLTERLTFEVADAMRLPYEDESFDCAWAIESLCHM
DRAKALGEAWRVLKPGGDLLVLESVVTEELTEPETALFETLYAANVPPRL
GEFFDIVSGAGFHTLSLKDLSANLAMTMNVFALGVYSRRAEFTERFGAEF
VDGLLAGLGSAQETLIRKTRFFMATLRKPAV
3D structure
PDB5gm1 Crystal structure and enantioselectivity of terpene cyclization in SAM-dependent methyltransferase TleD
ChainA
Resolution2.501 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SAH A G85 C86 G87 V108 Q112 D135 A136 I152 S154 H157 M158 G77 C78 G79 V100 Q104 D127 A128 I144 S146 H149 M150
BS02 SAH A V17 Y21 V36 H37 V9 Y13 V28 H29
BS03 SAH A Y244 S245 Y236 S237
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:5gm1, PDBe:5gm1, PDBj:5gm1
PDBsum5gm1
PubMed27613858
UniProtA0A077K7L1

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