Structure of PDB 5gkp Chain A

Receptor sequence
>5gkpA (length=235) Species: 6239 (Caenorhabditis elegans) [Search protein sequence]
SRSAEIMKHGYPGFTNVRTYEDFVLSYDYKTRTAHWVCEHLTPERLKGVD
RKLCEAKPDITFPQKFLSQNTDYKCSGFDRGALAAAGNHRKSQLAVDQTF
YLSNMSPQVGRGFNRDKWNDLEMHCRRVAKKMINSYIITGPLYLPKLEGD
GKKYIKYQVIGDNNVAVPTHFFKVALFEVTPGKFELESYILPNAVIEDTV
EISKFHVPLDAVERSAGLEIFARLDPKSIVKENGA
3D structure
PDB5gkp Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.30.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A R117 K140 C141 D145 R146 A148 A152 R181 N185 R51 K74 C75 D79 R80 A82 A86 R115 N119
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5gkp, PDBe:5gkp, PDBj:5gkp
PDBsum5gkp
PubMed27738134
UniProtQ95NM6|NUCG_CAEEL Endonuclease G, mitochondrial (Gene Name=cps-6)

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