Structure of PDB 5gih Chain A

Receptor sequence
>5gihA (length=210) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
PYTIELIQPEDGEAVIAMLKTFFFKDDPLNTFLDLGECKELEKYSLKPLP
DNCSYKAVNKKGEIIGVFLNGLMRRPSPDDVPEKAADSCEHPKFKKILSL
MDHVEEQFNIFDVYPDEELILDGKILSVDTNYRGLGIAGRLTERAYEYMR
ENGINVYHVLCSSHYSARVMEKLGFHEVFRMQFADYKPQGEVVFKPAAPH
VGIQVMAKEV
3D structure
PDB5gih Crystal Structure of Drosophila melanogaster E47D Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-phenylethylamine
ChainA
Resolution1.392 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.87: aralkylamine N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA A D46 L146 V148 R153 G154 G156 A158 S182 S186 K192 D26 L126 V128 R133 G134 G136 A138 S162 S166 K172
BS02 54W A F43 D47 N50 M121 K144 I145 L146 L180 F23 D27 N30 M101 K124 I125 L126 L160
Gene Ontology
Molecular Function
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups

View graph for
Molecular Function
External links
PDB RCSB:5gih, PDBe:5gih, PDBj:5gih
PDBsum5gih
PubMed
UniProtQ94521|DNAT_DROME Arylalkylamine N-acetyltransferase 1 (Gene Name=speck)

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