Structure of PDB 5gid Chain A

Receptor sequence
>5gidA (length=237) Species: 10116 (Rattus norvegicus) [Search protein sequence]
LSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMPLSMLPHLADLVSY
SIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDMSW
DCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAI
CIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQK
LADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFG
3D structure
PDB5gid Regulation of the vitamin D receptor by vitamin D lactam derivatives.
ChainA
Resolution2.151 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I238 K242 I256 K260 P412 E416 I56 K60 I74 K78 P230 E234
BS02 VDP A L220 L223 S233 I267 R270 S271 S274 W282 H393 Y397 F418 L38 L41 S51 I85 R88 S89 S92 W100 H211 Y215 F236 MOAD: Kd=769.2nM
PDBbind-CN: -logKd/Ki=6.11,Kd=769.2nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5gid, PDBe:5gid, PDBj:5gid
PDBsum5gid
PubMed27500498
UniProtP13053|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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