Structure of PDB 5ggk Chain A

Receptor sequence
>5ggkA (length=153) Species: 9606 (Homo sapiens) [Search protein sequence]
RVLDVEVYSSRSKVYVAVDGTTVLEDEAREQGRGIHVIVLNQATGHVMAK
RVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKDTAKALLRSL
GSQAGPALGWRDTWAFVGRKGGPVFGEKHSKSPALSSWGDPVLLKTDVPL
SSA
3D structure
PDB5ggk Carbohydrate-binding domain of the POMGnT1 stem region modulates O-mannosylation sites of alpha-dystroglycan
ChainA
Resolution1.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MBE A R129 Y152 D179 E180 R207 R33 Y56 D83 E84 R111 MOAD: Kd=0.29mM
PDBbind-CN: -logKd/Ki=3.54,Kd=0.29mM
External links
PDB RCSB:5ggk, PDBe:5ggk, PDBj:5ggk
PDBsum5ggk
PubMed27493216
UniProtQ8WZA1|PMGT1_HUMAN Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (Gene Name=POMGNT1)

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