Structure of PDB 5g6u Chain A

Receptor sequence
>5g6uA (length=131) Species: 9606 (Homo sapiens) [Search protein sequence]
SQGWKYFKGNFYYFSLIPKTWYSAEQFCVSRNSHLTSVTSESEQEFLYKT
AGGLIYWIGLTKAGMEGDWSWVDDTPFNKVQSVRFWIPGEPNNAGNNEHC
GNIKAPSLQAWNDAPCDKTFLFICKRPYVPS
3D structure
PDB5g6u Rational-Differential Design of Highly Specific Glycomimetic Ligands: Targeting DC-SIGN and Excluding Langerin Recognition.
ChainA
Resolution1.844 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 TRP A K257 G262 H294 K62 G67 H99
BS02 SGN A E285 N287 E293 K299 N307 E90 N92 E98 K104 N112 MOAD: ic50=0.22uM
BS03 CA A E285 N287 E293 N307 D308 E90 N92 E98 N112 D113
External links
PDB RCSB:5g6u, PDBe:5g6u, PDBj:5g6u
PDBsum5g6u
PubMed29272097
UniProtQ9UJ71|CLC4K_HUMAN C-type lectin domain family 4 member K (Gene Name=CD207)

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