Structure of PDB 5g5k Chain A

Receptor sequence
>5g5kA (length=333) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
HMQGSLMLDIGGTWLTAEDRQILRHPEVGGLIIFARNIEHPAQVRELCAA
IRAIRPDLLLAVDQEGGRVQRLRQGFVRLPAMRAIADNPNAEELAEHCGW
LMATEVQAVGLDLSFAPVLDLDHQRSAVVGSRAFEGDPERAALLAGAFIR
GMHAAGMAATGKHFPGHGWAEADSHVAIPEDARSLEEIRRSDLVPFARLA
GQLDALMPAHVIYPQVDPQPAGFSRRWLQEILRGELKFDGVIFSDDLSMA
GAHVVGDAASRIEAALAAGCDMGLVCNDRASAELALAALQRLKVTPPSRL
QRMRGKGYANTDYRQQPRWLEALSALRAAQLID
3D structure
PDB5g5k Catalytic Cycle of the N-Acetylglucosaminidase NagZ from Pseudomonas aeruginosa.
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.52: beta-N-acetylhexosaminidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NOK A D62 R131 H162 D244 D63 R132 H163 D245 BindingDB: Ki=300nM
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004563 beta-N-acetylhexosaminidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0009254 peptidoglycan turnover
GO:0046677 response to antibiotic
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:5g5k, PDBe:5g5k, PDBj:5g5k
PDBsum5g5k
PubMed28482153
UniProtQ9HZK0|NAGZ_PSEAE Beta-hexosaminidase (Gene Name=nagZ)

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