Structure of PDB 5g35 Chain A

Receptor sequence

>5g35A (length=114) Species: 4932 (Saccharomyces cerevisiae)

APKCIECHINIEMDPVLHDVFKLQVCKQCSKEHPEKYALLTKTECKEDYF
LTDPELNDEDLFHRLEKPNPHSGTFARMQLFVRCEVEAFAFKKWGGEEGL
DEEWQRREEGKAHR

3D structure

• PDB: 5g35 Structural Basis for Bulky Adduct DNA Lesion Recognition by the Nucleotide Excision Repair Protein Rad14.
• Chain: A
• Resolution: 2.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	T228 K229 T230 E231 E234 N256 H258 R264 M265 Q266	T41 K42 T43 E44 E47 N69 H71 R77 M78 Q79
BS02	dna	A	P241 F262 R294	P54 F75 R107
BS03	dna	A	P241 F262 R294 R301	P54 F75 R107 R114
BS04	dna	A	T228 K229 T230 E231 E234 N256 H258 R264 M265 Q266	T41 K42 T43 E44 E47 N69 H71 R77 M78 Q79
BS05	ZN	A	C191 C194 C213 C216	C4 C7 C26 C29

Gene Ontology

Molecular Function

• GO:0003684 damaged DNA binding

Biological Process

• GO:0006289 nucleotide-excision repair

External links

• PDB: RCSB:5g35, PDBe:5g35, PDBj:5g35
• PDBsum: 5g35
• PubMed: 27223336
• UniProt: P28519|RAD14_YEAST DNA repair protein RAD14 (Gene Name=RAD14)