Structure of PDB 5g0x Chain A

Receptor sequence
>5g0xA (length=370) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
TRRTAFFFDELCLWHAAGPHALTLPVGGWVQPPAAAGHAESPETKRRLKS
LLDVSGLTARLQLRSAPPASDEDLLRVHPAHYLERFKALSDAGGGSLGQD
APIGPGSYEIARLSAGLAIAALDAVLAGEADNAYSLSRPPGHHCLPDQAM
GFCFFANIAVAIEAAKARHGVERVAVLDWDVHHGNGTQAIYYRRDDVLSI
SLHQDGCFPPGYSGAEDIGEDRGRGFNLNVPLLPGGGHDAYMQAMQRIVL
PALERFRPQLIVVASGFDANAVDPLARMQLHSDSFRAMTAMVRDAAERHA
GGRLVVVHEGGYSEAYVPFCGLAVIEELSGVRSAVRDPLRDFIELQQPNA
AFRDFQRQRLEELAAQFGLC
3D structure
PDB5g0x Crystal Structure of a Histone Deacetylase Homologue from Pseudomonas aeruginosa.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D181 H183 D269 D180 H182 D268
BS02 ACT A H143 H144 D181 H183 Y313 H142 H143 D180 H182 Y312
Gene Ontology
Molecular Function
GO:0004407 histone deacetylase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0040029 epigenetic regulation of gene expression

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Molecular Function
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Biological Process
External links
PDB RCSB:5g0x, PDBe:5g0x, PDBj:5g0x
PDBsum5g0x
PubMed27951649
UniProtQ9HXM1|HDAH_PSEAE Histone deacetylase-like amidohydrolase (Gene Name=PA3774)

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