Structure of PDB 5fyg Chain A

Receptor sequence
>5fygA (length=422) Species: 2743 (Marinobacter nauticus) [Search protein sequence]
MPEFVETPIPDVNTLALEDIDVSNPFLYRQGQWRAYFKRLRDEAPVHYQK
NSPFGPFWSVTRFEDILFVDKSHDLFSAEPQIILGDPPEGLSVEMFIAMD
PPKHDVQRSSVQGVVAPKNLKEMEGLIRSRTGDVLDSLPTDKPFNWVPAV
SKELTGRMLATLLDFPYEERHKLVEWSDRMAGAASATGGEFADENAMFDD
AADMARSFSRLWRDKEARRAAGEEPGFDLISLLQSNKETKDLINRPMEFI
GNLTLLIVGGNDTTRNSMSGGLVAMNEFPREFEKLKAKPELIPNMVSEII
RWQTPLAYMRRIAKQDVELGGQTIKKGDRVVMWYASGNRDERKFDNPDQF
IIDRKDARNHMSFGYGVHRCMGNRLAELQLRILWEEILKRFDNIEVVEEP
ERVQSNFVRGYSRLMVKLTPNS
3D structure
PDB5fyg Structure-Guided Redesign of CYP153AM.aqfor the Improved Terminal Hydroxylation of Fatty Acids
ChainA
Resolution2.22 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) G234 G311 D314 T315 T316 C422 M423 G424 Q431 V460
Catalytic site (residue number reindexed from 1) G182 G259 D262 T263 T264 C370 M371 G372 Q379 V408
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A D122 F148 I149 H156 R160 L308 G311 G312 T315 M361 Y386 S414 F415 H420 C422 G424 A428 D70 F96 I97 H104 R108 L256 G259 G260 T263 M309 Y334 S362 F363 H368 C370 G372 A376
BS02 12H A Q133 V145 V310 G311 Q81 V93 V258 G259
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5fyg, PDBe:5fyg, PDBj:5fyg
PDBsum5fyg
PubMed
UniProtA1TY82

[Back to BioLiP]