Structure of PDB 5fy1 Chain A

Receptor sequence
>5fy1A (length=442) Species: 9606 (Homo sapiens) [Search protein sequence]
KDKLNPPTPSIYLENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLG
LFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWRCESNRSHTTI
AKYAQYQASSFQESLREENEKGPFKTIKFGTNIDLSDNKKWKLQLHELTK
LPAFARVVSAGNLLTHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSV
NINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDLYEANV
PVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAVER
YEWNKLKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQT
LREALVAAGKEVIWHGRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYI
VHCHDCARKTSKSLENFVVLEQYKMEDLIQVYDQFTLALSLS
3D structure
PDB5fy1 Crystal Structure of Jmjc Domain of Human Histone Demethylase Uty in Complex with N08619B
ChainA
Resolution1.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.68: [histone H3]-trimethyl-L-lysine(27) demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C1278 C1281 C1305 C1308 C376 C379 C403 C406
BS02 MN A H1093 E1095 H1173 H191 E193 H271
BS03 0R0 A M944 H976 M65 H97
BS04 0R0 A T1292 E1294 N1318 T390 E392 N416
External links
PDB RCSB:5fy1, PDBe:5fy1, PDBj:5fy1
PDBsum5fy1
PubMed
UniProtO14607|UTY_HUMAN Histone demethylase UTY (Gene Name=UTY)

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