Structure of PDB 5fw5 Chain A

Receptor sequence
>5fw5A (length=139) Species: 9606 (Homo sapiens) [Search protein sequence]
SMVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNG
KPADAVYGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLS
NNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVF
3D structure
PDB5fw5 Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication.
ChainA
Resolution1.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F15 R17 Q18 T21 L22 Q25 R32 F33 E117 K123 F124 F16 R18 Q19 T22 L23 Q26 R33 F34 E118 K124 F125
External links
PDB RCSB:5fw5, PDBe:5fw5, PDBj:5fw5
PDBsum5fw5
PubMed27383630
UniProtQ13283|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (Gene Name=G3BP1)

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