Structure of PDB 5fve Chain A

Receptor sequence
>5fveA (length=367) Species: 85962 (Helicobacter pylori 26695) [Search protein sequence]
MKISVSKNDLENALRYLQAFLDKKDASSIASHIHLEVIKEKLFLKASDSD
IGLKSYIFTQSSDKEGVGTINGKKFLDIISCLKDSNIILETKDDSLAIKQ
NKSSFKLPMFDADEFPEFPVIDPKVSIEVNAPFLVDAFKKIAPVIEQTSH
KRELAGILMQFDQKHQTLSVVGTDTKRLSYTQLEKISIHSTEEDISCILP
KRALLEILKLFYENFSFKSDGMLAVIENEMHTFFTKLIDGNYPDYQKILP
KEYISSFTLGKEEFKESIKLCSSLSSTIKLTLEKNNALFESLDSEHSETA
KTSVEIEKGLDIEKAFHLGVNAKFFLEALNALGTTQFVLRCNEPSSPFLI
QESLNAKISTLMMPITL
3D structure
PDB5fve Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization.
ChainA
Resolution2.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2HO A T175 K176 R177 I248 P347 L368 M370 T175 K176 R177 I248 P347 L361 M363
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006260 DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0009360 DNA polymerase III complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5fve, PDBe:5fve, PDBj:5fve
PDBsum5fve
PubMed29324718
UniProtO25242|DPO3B_HELPY Beta sliding clamp (Gene Name=dnaN)

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