Structure of PDB 5fsy Chain A

Receptor sequence
>5fsyA (length=232) Species: 5691 (Trypanosoma brucei) [Search protein sequence]
EFVTYSGEESPTRTRILSAALSPAERAIFDVPIEKWLSIDRSSLSGWKCA
VPRPVTIEQLRPVDPSDAILRHIALYRGPVTDLQLDAIVNAANTRCLGGG
GVDGAIHRVAGPLLLRECATFNGCQTGECRLTKGYQLPARYVLHTVGPVG
ERPDMLRKCYRSILSLALKNGLRSIGFCCVSTGVYGYPLLPATRIALGET
RKFLEEHGGALDMCCFACFQEDEYKTYEKCVG
3D structure
PDB5fsy Proximal Adp-Ribose Hydrolysis in Trypanosomatids is Catalyzed by a Macrodomain.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AR6 A A120 N122 G129 G130 V131 D132 C208 S210 G212 V213 Y214 F248 Q249 E252 A91 N93 G100 G101 V102 D103 C179 S181 G183 V184 Y185 F219 Q220 E223 MOAD: Ka=790000M^-1
PDBbind-CN: -logKd/Ki=5.89,Kd=1.3uM
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding

View graph for
Molecular Function
External links
PDB RCSB:5fsy, PDBe:5fsy, PDBj:5fsy
PDBsum5fsy
PubMed27064071
UniProtC9ZP98

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