Structure of PDB 5fs5 Chain A

Receptor sequence
>5fs5A (length=158) Species: 364106 (Escherichia coli UTI89) [Search protein sequence]
FACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPE
TITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTD
KPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNANSDDFQFVWNIYA
NNDVVVPT
3D structure
PDB5fs5 Mutation of Tyr137 of the universal Escherichia coli fimbrial adhesin FimH relaxes the tyrosine gate prior to mannose binding.
ChainA
Resolution1.42 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KGM A F1 I13 N46 D47 Y48 D54 Q133 N135 D140 F1 I13 N46 D47 Y48 D54 Q133 N135 D140 MOAD: Kd=206.4nM
PDBbind-CN: -logKd/Ki=6.69,Kd=206.4nM
Gene Ontology
Cellular Component
GO:0009289 pilus

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Biological Process
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Cellular Component
External links
PDB RCSB:5fs5, PDBe:5fs5, PDBj:5fs5
PDBsum5fs5
PubMed28250938
UniProtP08191|FIMH_ECOLI Type 1 fimbrin D-mannose specific adhesin (Gene Name=fimH)

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