Structure of PDB 5fpe Chain A

Receptor sequence
>5fpeA (length=377) Species: 9606 (Homo sapiens) [Search protein sequence]
GPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGD
AAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKV
QVEYKGETKTFFPEEISSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDS
QRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGEKNVLIFDLGGGTF
DVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGP
NKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEEL
NADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFN
GKELNKSINPDEAVAYGAAVQAAILIG
3D structure
PDB5fpe Detection of Secondary Binding Sites in Proteins Using Fragment Screening.
ChainA
Resolution1.96 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D10 K71 E175 D201
Catalytic site (residue number reindexed from 1) D7 K68 E172 D194
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3TR A K273 S277 G341 K266 S270 G334
BS02 3TR A Y149 D208 A225 Y146 D201 A218
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0140662 ATP-dependent protein folding chaperone

View graph for
Molecular Function
External links
PDB RCSB:5fpe, PDBe:5fpe, PDBj:5fpe
PDBsum5fpe
PubMed26655740
UniProtP54652|HSP72_HUMAN Heat shock-related 70 kDa protein 2 (Gene Name=HSPA2)

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