Structure of PDB 5flg Chain A

Receptor sequence
>5flgA (length=253) Species: 1423 (Bacillus subtilis) [Search protein sequence]
EETFYSVRMRASMNGSDGGKHISGGERLIPFHEMKHTVNALLEKGLSHSR
GKPDFMQIQFEEVHESIKTIQPLPVHTNEVSCPEEGQKLARLLLEKEGVS
RDVIEKAYEQIPEWSDVRGAVLFDIHTGKRMDQTKEKGVRVSRMDWPDAN
FEKWALHSHVPAHSRIKEALALASKVSRHPAVVAELCWSDDPDYITGYVA
GKKMGYQRITAMKEYGTEEGCRVFFIDGSNDVNTYIHDLEKQPILIEWEE
DHD
3D structure
PDB5flg Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters.
ChainA
Resolution2.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.2.1.14: 6-carboxyhexanoate--CoA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PML A R170 I171 S194 Y199 Y211 R213 R165 I166 S189 Y194 Y206 R208
BS02 ANP A H26 S28 G29 E31 K49 H53 R123 G124 A125 R145 V146 L177 D195 R227 H21 S23 G24 E26 K44 H48 R118 G119 A120 R140 V141 L172 D190 R222
BS03 MG A D195 D196 D190 D191
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0042410 6-carboxyhexanoate-CoA ligase activity
Biological Process
GO:0009102 biotin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5flg, PDBe:5flg, PDBj:5flg
PDBsum5flg
PubMed28414710
UniProtP53559|BIOW_BACSU 6-carboxyhexanoate--CoA ligase (Gene Name=bioW)

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