Structure of PDB 5fi5 Chain A

Receptor sequence
>5fi5A (length=342) Species: 4058 (Catharanthus roseus) [Search protein sequence]
PVKAFGLAAKDSSGLFSPFNFSRRATGEHDVQLKVLYCGTCQYDREMSKN
KFGFTSYPYVLGHEIVGEVTEVGSKVQKFKVGDKVGVASIIETCGKCEMC
TNEVENYCPEAGSIDSNYGACSNIAVINENFVIRWPENLPLDSGVPLLCA
GITAYSPMKRYGLDKPGKRIGIAGLGGLGHVALRFAKAFGAKVTVISSSL
KKKREAFEKFGADSFLVSSNPEEMQGAAGTLDGIIDTIPGNHSLEPLLAL
LKPLGKLIILGAPEMPFEVPAPSLLMGGKVMAASTAGSMKEIQEMIEFAA
EHNIVADVEVISIDYVNTAMERLDNSDVRYRFVIDIGNTLKS
3D structure
PDB5fi5 Structural investigation of heteroyohimbine alkaloid synthesis reveals active site elements that control stereoselectivity.
ChainA
Resolution2.25 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C54 Q55 Y56 E59 H76 E77 C107 C110 C113 C121 G125 C162 R344
Catalytic site (residue number reindexed from 1) C41 Q42 Y43 E46 H63 E64 C94 C97 C100 C108 G112 C149 R331
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C107 C110 C113 C121 C94 C97 C100 C108
BS02 ZN A C54 H76 E77 C162 C41 H63 E64 C149
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0045551 cinnamyl-alcohol dehydrogenase activity
GO:0046872 metal ion binding
Biological Process
GO:0009809 lignin biosynthetic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5fi5, PDBe:5fi5, PDBj:5fi5
PDBsum5fi5
PubMed27418042
UniProtA0A0F6SD02

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