Structure of PDB 5fg6 Chain A

Receptor sequence
>5fg6A (length=118) Species: 9606 (Homo sapiens) [Search protein sequence]
RLTPLTVLLRSVLDQLQDKDPARIFAQPVSLKEVPDYLDHIKHPMDFATM
RKRLEAQGYKNLHEFEEDFDLIIDNCMKYNARDTVFYRAAVRLRDQGGVV
LRQARREVDSIGLEEASG
3D structure
PDB5fg6 Crystal structure of the bromodomain of human BRD1 (BRPF2) in complex with OF-1 chemical probe
ChainA
Resolution1.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5XE A I586 F587 V591 E595 F648 I24 F25 V29 E33 F86 BindingDB: IC50=128nM,Kd=500nM
External links
PDB RCSB:5fg6, PDBe:5fg6, PDBj:5fg6
PDBsum5fg6
PubMed
UniProtO95696|BRD1_HUMAN Bromodomain-containing protein 1 (Gene Name=BRD1)

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