Structure of PDB 5fg5 Chain A

Receptor sequence
>5fg5A (length=114) Species: 9606 (Homo sapiens) [Search protein sequence]
MEMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDF
FTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQG
GAVLRQARRQAEKM
3D structure
PDB5fg5 Crystal structure of the bromodomain of human BRPF1 in complex with PFI-4 chemical probe
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5XF A I652 E655 V657 P658 E661 V662 Y707 N708 F714 I27 E30 V32 P33 E36 V37 Y82 N83 F89 BindingDB: IC50=50nM,Kd=13nM
External links
PDB RCSB:5fg5, PDBe:5fg5, PDBj:5fg5
PDBsum5fg5
PubMed
UniProtP55201|BRPF1_HUMAN Peregrin (Gene Name=BRPF1)

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