Structure of PDB 5fg4 Chain A

Receptor sequence
>5fg4A (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
MQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFT
MKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGA
VLRQARRQAEKMG
3D structure
PDB5fg4 Crystal structure of the bromodomain of human BRPF1 in complex with OF-1 chemical probe
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5XE A I652 F653 V657 P658 E661 V662 Y707 N708 F714 I25 F26 V30 P31 E34 V35 Y80 N81 F87 BindingDB: IC50=270nM,Kd=100nM
External links
PDB RCSB:5fg4, PDBe:5fg4, PDBj:5fg4
PDBsum5fg4
PubMed
UniProtP55201|BRPF1_HUMAN Peregrin (Gene Name=BRPF1)

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