Structure of PDB 5ffg Chain A

Receptor sequence
>5ffgA (length=591) Species: 9606 (Homo sapiens) [Search protein sequence]
FNLDVDSPAEYSGPEGSYFGFAVDFFVPSRMFLLVGAPKANTTQPGIVEG
GQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQD
KILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQG
FCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIK
YNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMV
YIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDR
GSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQD
GFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSGCPP
SFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPS
ILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKL
KQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKL
TPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHIL
3D structure
PDB5ffg Force interacts with macromolecular structure in activation of TGF-beta.
ChainA
Resolution2.25 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D284 N286 D288 Y290 D292 D281 N283 D285 Y287 D289
BS02 CA A D349 D351 D353 F355 D357 D346 D348 D350 F352 D354
BS03 CA A D414 D416 N418 Y420 D422 D411 D413 N415 Y417 D419
BS04 CA A D230 N232 D234 I236 D238 D227 N229 D231 I233 D235
Gene Ontology
Cellular Component
GO:0008305 integrin complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5ffg, PDBe:5ffg, PDBj:5ffg
PDBsum5ffg
PubMed28117447
UniProtP06756|ITAV_HUMAN Integrin alpha-V (Gene Name=ITGAV)

[Back to BioLiP]