Structure of PDB 5fff Chain A

Receptor sequence
>5fffA (length=257) Species: 39639 (Narcissus pseudonarcissus) [Search protein sequence]
MSLEKRWSLEGTTALVTGGTKGIGHAIVEELVGFGARVYTCSRNEAELRK
CLQEWENLKYDVTGSVCDVSSRTEREKLAEEVSSVFNGKLNILINNAGGY
VNKPIDGFTAEDFSFLVAVNLESAFHLCQLAHPMLKASGTGSIVHISSCC
AQIAIPGHSIYSSTKGAINQLTRNLACEWAKDNIRTNSIAPGAIRTPGTE
SFVIDKDALDREVSRVPFGRIGEPEEVASLAAFLCMPSASYITGQVICVD
GGRTING
3D structure
PDB5fff Identification of a Noroxomaritidine Reductase with Amaryllidaceae Alkaloid Biosynthesis Related Activities.
ChainA
Resolution1.501 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K220
Catalytic site (residue number reindexed from 1) K206
Enzyme Commision number 1.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A G32 T34 G36 I37 R57 C81 D82 V83 N110 I160 Y175 K179 P205 A207 I208 T210 G212 T213 G18 T20 G22 I23 R43 C67 D68 V69 N96 I146 Y161 K165 P191 A193 I194 T196 G198 T199
BS02 5XC A Y114 H172 Y100 H158 MOAD: ic50=425uM
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
Biological Process
GO:0009820 alkaloid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5fff, PDBe:5fff, PDBj:5fff
PDBsum5fff
PubMed27252378
UniProtA0A1A9TAK5|NR_NARPS Noroxomaritidine/norcraugsodine reductase (Gene Name=NR)

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