Structure of PDB 5fcf Chain A

Receptor sequence
>5fcfA (length=397) Species: 190485 (Xanthomonas campestris pv. campestris str. ATCC 33913) [Search protein sequence]
TQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALL
IGAGTSLRYFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQL
PVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTA
IRDAGAIIDGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQL
VRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQHLRAGELVLIDT
GCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEA
VDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQ
PGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA
3D structure
PDB5fcf Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases.
ChainA
Resolution1.85 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H234 D251 D262 T264 H327 H331 H338 E360 V364 R372 E374
Catalytic site (residue number reindexed from 1) H232 D249 D260 T262 H325 H329 H336 E358 V362 R370 E372
Enzyme Commision number 3.4.13.9: Xaa-Pro dipeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H142 R146 A152 I153 H140 R144 A150 I151
BS02 MN A D262 H331 S358 E360 E374 D260 H329 S356 E358 E372
BS03 MN A F221 D251 D262 E374 F219 D249 D260 E372
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5fcf, PDBe:5fcf, PDBj:5fcf
PDBsum5fcf
PubMed27816563
UniProtQ8P839

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