Structure of PDB 5faw Chain A

Receptor sequence
>5fawA (length=803) Species: 207559 (Oleidesulfovibrio alaskensis G20) [Search protein sequence]
GLVPRGSHMGIPDGPTPRHVKLKENFLKQVPSITVQRAVAITKIAKENPG
LPKPLLRAKTFRYCCETAPLVIQDHELIVGSPNGAPRAGAFSPEVAWRWL
QDELDTIGSRPQDPFYISEEDKKVLREEVFPFWQNKSVDEFCEGQYREAD
LWEMSGESFVSDCSYHAVNGGGDSNPGYDVILMKKGMLDIQREAREKLEQ
LDYANPEDIDKIYFYKSVIETAEGVMIYARRLSAYAAELAARETDPRRKA
ELQKISEVNARVPAHAPSNFWEAIQAVWTVESLLVVEENQTGMSIGRVDQ
YMYPFYRADIDSGRLTEYEAFDLAGCMLVKMSEMMWITSEGASKFFAGYQ
PFVNMCVGGVTREGHDATNDLTYMLMDAVRHVRIYQPTLATRVHNKSPQK
YLKKIVDVIRSGMGFPAVHFDDAHIKMMLAKGVSIEDARDYCLMGCVEPQ
KSGRLYQWASTGYTQWPICIELVLNHGVPLWYGKKVTPDMGDLSQYDTYE
KFEAAVKEQIRWITKNTSVATVISQRAHRELAPKPLMSLMYEGCMESGRD
VSAGGAMYNFGPGVVWSGLATYVDSMAAIKKLVYDDRKYTLAQLNEALKA
DFAGYDQILADCLAAPKYGNDDDYADMIAADLVHFTETEHRKYKTLYSVL
SHGTLSISNNTPFGQLLGASANGRRAWMPLSDGISPTQGADYKGPTAIIK
SVSKMANDNMNIGMVHNFKLMSGLLDTPEGENGLITLIRTACMLGNGEMQ
FNYLDNELLLDAQKHPEKYRDLVVRVAGYSAFFVELCKDVQDEIISRTML
HGF
3D structure
PDB5faw Molecular Basis of C-N Bond Cleavage by the Glycyl Radical Enzyme Choline Trimethylamine-Lyase.
ChainA
Resolution1.852 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F395 G488 C489 G821
Catalytic site (residue number reindexed from 1) F352 G445 C446 G778
Enzyme Commision number 4.3.99.4: choline trimethylamine-lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CHT A Y208 D216 F395 G488 C489 E491 Y165 D173 F352 G445 C446 E448
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0016840 carbon-nitrogen lyase activity
GO:0033265 choline binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0042426 choline catabolic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5faw, PDBe:5faw, PDBj:5faw
PDBsum5faw
PubMed27642068
UniProtQ30W70|CUTC_OLEA2 Choline trimethylamine-lyase (Gene Name=cutC)

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