Structure of PDB 5f8w Chain A

Receptor sequence
>5f8wA (length=149) Species: 151218 (Crenomytilus grayanus) [Search protein sequence]
TTFLIKHKASGKFLHPYGGSSNPANNTKLVLHSDIHERMYFQFDVVDERW
GYIKHVASGKIVHPYGGQANPPNETNMVLHQDRHDRALFAMDFFNDNIMH
KGGKYIHPKGGSPNPPNNTETVIHGDKHAAMEFIFVSPKNKDKRVLVYA
3D structure
PDB5f8w A Multivalent Marine Lectin from Crenomytilus grayanus Possesses Anti-cancer Activity through Recognizing Globotriose Gb3
ChainA
Resolution1.56 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL A E75 H108 K110 G111 G112 V123 H125 D127 H129 E74 H107 K109 G110 G111 V122 H124 D126 H128 MOAD: Kd=15uM
BS02 GLA A H16 Y18 G19 G20 H33 D35 H37 N119 H15 Y17 G18 G19 H32 D34 H36 N118 MOAD: Kd=51uM
BS03 GLA A N27 H64 Y66 G67 G68 H81 D83 H85 N26 H63 Y65 G66 G67 H80 D82 H84 MOAD: Kd=51uM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:5f8w, PDBe:5f8w, PDBj:5f8w
PDBsum5f8w
PubMed27010847
UniProtH2FH31|LEC_CREGR Galactose-binding lectin

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