Structure of PDB 5f8f Chain A

Receptor sequence
>5f8fA (length=353) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
METTEEFGNRFVAAIDSAGLAILVSVGHQTGLLDTMAGLPPATSMEIAEA
AGLEERYVREWLGGMTTGQIVEYDAGSSTYSLPAHRAGMLTRAAGPDNLA
VIAQFVSLLGEVEQKVIRCFREGGGVPYSEYPRFHKLMAEMSGMVFDAAL
IDVVLPLVDGLPDRLRSGADVADFGCGSGRAVKLMAQAFGASRFTGIDFS
DEAVAAGTEEAARLGLANATFERHDLAELDKVGAYDVITVFDAIHDQAQP
ARVLQNIYRALRPGGVLLMVDIKASSQLEDNVGVPLSTYLYTTSLMHCMT
VSLALDGAGLGTVWGRQLATSMLADAGFTDVTVAEIESDVLNNYYIARKL
EHH
3D structure
PDB5f8f Crystal structure of Rv2258c from Mycobacterium tuberculosis H37Rv, an S-adenosyl-l-methionine-dependent methyltransferase
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SFG A Y132 S146 F150 G179 G181 D202 F203 D229 L230 F245 D246 Q251 Y128 S142 F146 G175 G177 D198 F199 D225 L226 F241 D242 Q247
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
Biological Process
GO:0032259 methylation
GO:0071456 cellular response to hypoxia
Cellular Component
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5f8f, PDBe:5f8f, PDBj:5f8f
PDBsum5f8f
PubMed26772148
UniProtO53532|Y2258_MYCTU S-adenosylmethionine-dependent methyltransferase Rv2258c (Gene Name=Rv2258c)

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