Structure of PDB 5f7u Chain A

Receptor sequence

>5f7uA (length=1059) Species: 169963 (Listeria monocytogenes EGD-e)

DGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVE
WTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGT
AYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFE
DLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYR
MEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFG
ERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSD
FHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDIT
GKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSD
EETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIV
LWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNG
ILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTNGGEMVWGRDTTFSNGEK
GQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQT
STFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAF
APIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPY
IYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQE
GQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPM
NMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISV
SEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNE
ATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTA
SDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATR
TVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGI
NFDHVVIKK

3D structure

• PDB: 5f7u Structure to function of an alpha-glucan metabolic pathway that promotes Listeria monocytogenes pathogenesis.
• Chain: A
• Resolution: 1.7 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GLC	A	F973 T991	F941 T959
BS02	GLC	A	D798 N801 H805 Y813 Y814	D766 N769 H773 Y781 Y782
BS03	GLC	A	T443 Y444 Y496 E497 Q498	T411 Y412 Y464 E465 Q466
BS04	GLC	A	H985 G996 W1051 N1083	H953 G964 W1019 N1051
BS05	GLC	A	D998 V1027 A1080 G1081	D966 V995 A1048 G1049
BS06	GLC	A	W71 N103 N104	W39 N71 N72
BS07	GLC	A	N301 W528 R614 D630 F663 E691	N269 W496 R582 D598 F631 E659
BS08	GLC	A	E428 W484 N565 W627 D630 F663 H689	E396 W452 N533 W595 D598 F631 H657
BS09	GLC	A	N400 Q429 E433	N368 Q397 E401
BS10	MG	A	E970 E972 T989 G992 D1085	E938 E940 T957 G960 D1053
BS11	MG	A	D847 S850	D815 S818
BS12	MG	A	E401 D403 D407	E369 D371 D375
BS13	MG	A	Y851 D852	Y819 D820

Gene Ontology

Molecular Function

• GO:0003824 catalytic activity
• GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0030246 carbohydrate binding
• GO:0046872 metal ion binding

Biological Process

• GO:0005975 carbohydrate metabolic process

External links

• PDB: RCSB:5f7u, PDBe:5f7u, PDBj:5f7u
• PDBsum: 5f7u
• PubMed: 27819654
• UniProt: Q8Y4J2