Structure of PDB 5f56 Chain A

Receptor sequence

>5f56A (length=703) Species: 1299 (Deinococcus radiodurans)

SRPAHWLLAPPASRDALLATMREWQVSPPVAQVLCGRDLRTELLALPLEL
TPNPALREAARHIVAAVREGKRIRIHGDYDADGVSATATLVLGLRAIGAN
VHGFIPHRLNEGYGIHPDRVPEHAAAADLVVTVDCGVSNLDEVKSLLATG
TEVVVTDHHAPGENFPECLVVHPHLTPDYDPDRHNLTGAGVAYHLLWAVY
EELGRPEPRALLPLATLGTVADVAPLLGENRALVRAGLAEMARTELPGLR
ALMNEKRVRQPTARDVAFILAPRINAAGRMGEADRALELLTTPSDHEAKS
LAAYLEIRNQERRKIQDDMFAQALQLADPNDPALVLTHDDWHAGVMGIVA
SKLVETFNRPVYIVAQGKGSVRSTPGISAVQGLRESRDLLGRFGGHPGAA
GFSLDPQNFGALRERIHGYVRQFPTPVPAVRLDAPLPVAALTPELLSELS
ILEPFGEGNPRPLWHLRGPLTDTRLVGKQGDVLQFRFGGVKGMKYSERDD
AAGERDVAAELALNEWKGRTSLELHAAALRPLAPLALAGTEEGLPTLPRL
NPREAMTFLKTGAAAYAEQGVATYLRDNVPGLTLLDTNAPHPGGDLILYG
LPPESALRRWLHEAQEQGGRVAFALGPKTLAELDAALTLAKLLPDSHTEA
AQEAAADAYRSWQWAHHYRVLNDAGWSASVYAMLGLPVPAALPKAAEALA
LAA

3D structure

• PDB: 5f56 Structural basis for DNA 5 -end resection by RecJ
• Chain: A
• Resolution: 2.3 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	Y114 R265 F269 P273 N276 R280 R313 R314 E356 R373 G395 H397 G402 V477 G478 V483 Q485 K492 M494 Y496 N515 W517	Y113 R264 F268 P272 N275 R279 R312 R313 E355 R372 G394 H396 G401 V476 G477 V482 Q484 K491 M493 Y495 N514 W516
BS02	peptide	A	P553 V572 Y575 L576 Y600 G627 P628 K629 T630	P552 V571 Y574 L575 Y599 G626 P627 K628 T629
BS03	MN	A	D79 D81 D135	D78 D80 D134
BS04	MN	A	D83 D135 H159 D223	D82 D134 H158 D222

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0004527 exonuclease activity
• GO:0008409 5'-3' exonuclease activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006281 DNA repair
• GO:0006310 DNA recombination

External links

• PDB: RCSB:5f56, PDBe:5f56, PDBj:5f56
• PDBsum: 5f56
• PubMed: 27058167
• UniProt: D0EM60