Structure of PDB 5f4l Chain A

Receptor sequence
>5f4lA (length=336) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
KTTLFCASDAKAYEKEVHNVWATHACVPTDPNPQEMVLANVTENFNMWKN
DMVEQMHEDIISLWDESLKPCVKLTGGSAITQACPKVSFDPIPLHYCAPA
GFAILKCNNKTFNGTGPCRNVSTVQCTHGIKPVVSTQLLLNGSLAEEEII
IRSENLTNNAKTIIVHLNESVNIVCTRPNNIRQAHCNINESKWNNTLQKV
GEELAKHFPSKTIKFEPSSGGDLEITTHSFNCRGEFFYCNTSDLFNGTYR
NGTYNHTGRSSNGTITLQCKIKQIINMWQEVGRAIYAPPIEGEITCNSNI
TGLLLLRDDTETFRPGGGDMRDNWRSELYKYKVVEI
3D structure
PDB5f4l Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5VE A S256 E370 S375 F376 F382 N425 M426 W427 G473 M475 S135 E224 S229 F230 F236 N276 M277 W278 G318 M320 PDBbind-CN: -logKd/Ki=7.62,Kd=0.024uM
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:5f4l, PDBe:5f4l, PDBj:5f4l
PDBsum5f4l
PubMed26985324
UniProtC6G099

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