Structure of PDB 5f2m Chain A

Receptor sequence
>5f2mA (length=324) Species: 301447 (Streptococcus pyogenes serotype M1) [Search protein sequence]
TLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKEPTVEQIEEL
KSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTTS
RLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSE
CRAEDIPFYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVD
VLKVEVPVNMKFVEGFADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGV
SAKLFQDTLVFAAESGAKFNGVLCGRATWAGSVKVYIEEGPQAAREWLRT
EGFKNIDELNKVLDKTASPWTEKM
3D structure
PDB5f2m NON-STEREOSPECIFIC SUBSTRATE CLEAVAGE BY TAGATOSE-BISPHOSPHATE CLASS I ALDOLASE
ChainA
Resolution1.92 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 4.1.2.40: tagatose-bisphosphate aldolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M2P A D27 Q28 R29 G30 A31 T94 E163 K205 S249 A250 L275 G277 R278 D25 Q26 R27 G28 A29 T92 E161 K203 S247 A248 L273 G275 R276
BS02 CA A E238 T241 E236 T239
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0009024 tagatose-6-phosphate kinase activity
GO:0009025 tagatose-bisphosphate aldolase activity
GO:0016829 lyase activity
GO:0061595 6-deoxy-6-sulfofructose-1-phosphate aldolase activity
Biological Process
GO:0005988 lactose metabolic process
GO:0019512 lactose catabolic process via tagatose-6-phosphate
GO:1902777 6-sulfoquinovose(1-) catabolic process
GO:2001059 D-tagatose 6-phosphate catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5f2m, PDBe:5f2m, PDBj:5f2m
PDBsum5f2m
PubMed
UniProtP63705|LACD2_STRP1 Tagatose 1,6-diphosphate aldolase 2 (Gene Name=lacD2)

[Back to BioLiP]