Structure of PDB 5f2l Chain A

Receptor sequence
>5f2lA (length=324) Species: 301447 (Streptococcus pyogenes serotype M1) [Search protein sequence]
TLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKEPTVEQIEEL
KSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTTS
RLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSE
CRAEDIPFYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVD
VLKVEVPVNMKFVEGFADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGV
SAKLFQDTLVFAAESGAKFNGVLCGRATWAGSVKVYIEEGPQAAREWLRT
EGFKNIDELNKVLDKTASPWTEKM
3D structure
PDB5f2l NON-STEREOSPECIFIC SUBSTRATE CLEAVAGE BY TAGATOSE-BISPHOSPHATE CLASS I ALDOLASE
ChainA
Resolution1.755 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.2.40: tagatose-bisphosphate aldolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M2P A Q28 R29 G30 A31 T94 L127 E163 K205 S249 A250 R278 Q26 R27 G28 A29 T92 L125 E161 K203 S247 A248 R276
BS02 CA A E238 T241 E236 T239
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0009024 tagatose-6-phosphate kinase activity
GO:0009025 tagatose-bisphosphate aldolase activity
GO:0016829 lyase activity
GO:0061595 6-deoxy-6-sulfofructose-1-phosphate aldolase activity
Biological Process
GO:0005988 lactose metabolic process
GO:0019512 lactose catabolic process via tagatose-6-phosphate
GO:1902777 6-sulfoquinovose(1-) catabolic process
GO:2001059 D-tagatose 6-phosphate catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5f2l, PDBe:5f2l, PDBj:5f2l
PDBsum5f2l
PubMed
UniProtP63705|LACD2_STRP1 Tagatose 1,6-diphosphate aldolase 2 (Gene Name=lacD2)

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