Structure of PDB 5f2f Chain A

Receptor sequence
>5f2fA (length=158) Species: 1206108 (Escherichia coli J96) [Search protein sequence]
FACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYPE
TITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTD
KPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNSDDFQFVWNIYA
NNDVVVPT
3D structure
PDB5f2f Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI.
ChainA
Resolution1.665 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5U7 A F1 I13 N46 D47 Y48 I52 D54 Q133 N135 D140 F1 I13 N46 D47 Y48 I52 D54 Q133 N135 D140 PDBbind-CN: -logKd/Ki=6.92,IC50=0.12uM
Gene Ontology
Cellular Component
GO:0009289 pilus

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Biological Process
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Cellular Component
External links
PDB RCSB:5f2f, PDBe:5f2f, PDBj:5f2f
PDBsum5f2f
PubMed26812660
UniProtP08191|FIMH_ECOLI Type 1 fimbrin D-mannose specific adhesin (Gene Name=fimH)

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