Structure of PDB 5f25 Chain A

Receptor sequence
>5f25A (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMK
DKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMM
SKERLLALKRSMS
3D structure
PDB5f25 Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor.
ChainA
Resolution1.68 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5TU A F44 F45 V49 I53 Y99 N100 Y106 F23 F24 V28 I32 Y78 N79 Y85 MOAD: Kd=9.1uM
PDBbind-CN: -logKd/Ki=5.04,Kd=9.1uM
BindingDB: Kd=9100nM,IC50=9338nM
External links
PDB RCSB:5f25, PDBe:5f25, PDBj:5f25
PDBsum5f25
PubMed26914985
UniProtQ9H8M2|BRD9_HUMAN Bromodomain-containing protein 9 (Gene Name=BRD9)

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