Structure of PDB 5f24 Chain A

Receptor sequence
>5f24A (length=260) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
TDKTLQQIDKLICSWLKQIDNVIPQLIMEMTETKRHRFDLVTNVDKQIQQ
QFQQFLATYFPEHQLLAEEKMITNEINHLWIMDPIDGTANLVKQQEDYCI
ILAYFYEGKPMLSYVYDYPHKKLYKAIRGEGAFCNGFKMEEPPSLKLEDA
IISFNAQVMNLDTVQDLFDASFSYRLVGACGLDSMRVAKGQFGAHINTNP
KPWDIAAQFLFAELLNLKMTTLDGKAIDHLKGAPFIISNKACHETVLKIL
NANGGYQKYR
3D structure
PDB5f24 Structural elucidation of the NADP(H) phosphatase activity of staphylococcal dual-specific IMPase/NADP(H) phosphatase
ChainA
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E70 D88 I90 D91 T93 D209
Catalytic site (residue number reindexed from 1) E68 D83 I85 D86 T88 D204
Enzyme Commision number 3.1.3.25: inositol-phosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D88 D91 D209 D83 D86 D204
BS02 CA A E70 D88 I90 E68 D83 I85
BS03 IPD A D91 G92 G183 C185 N202 D86 G87 G178 C180 N197
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008934 inositol monophosphate 1-phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0006020 inositol metabolic process
GO:0007165 signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:5f24, PDBe:5f24, PDBj:5f24
PDBsum5f24
PubMed26894675
UniProtQ2FVV7

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