Structure of PDB 5f1r Chain A

Receptor sequence
>5f1rA (length=229) Species: 169963 (Listeria monocytogenes EGD-e) [Search protein sequence]
NAQAEEFKKYLETNGIKPKQFHKKELIFNQWDPQEYCIFLYDGITKLTSI
SENGTIMNLQYYKGAFVIMSGFIDTETSVGYYNLEVISEQATAYVIKINE
LKELLSKNLTHFFYVFQTLQKQVSYSLAKFNDFSINGKLGSICGQLLILT
YVYGKETPDGIKITLDNLTMQELGSSAVSRIISKLKQEKVIVYKNSCFYV
QNLDYLKRYAPKLDEWFYLACPATWGKLN
3D structure
PDB5f1r Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 42O A Y62 F67 K122 Y126 I149 W224 C229 Y61 F66 K121 Y125 I148 W216 C221 MOAD: Kd=1uM
PDBbind-CN: -logKd/Ki=6.00,Kd=1uM
BindingDB: IC50=4500nM
BS02 42O A F131 F134 F130 F133 MOAD: Kd=1uM
PDBbind-CN: -logKd/Ki=6.00,Kd=1uM
BindingDB: IC50=4500nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5f1r, PDBe:5f1r, PDBj:5f1r
PDBsum5f1r
PubMed26991105
UniProtP22262|PRFA_LISMO Listeriolysin regulatory protein (Gene Name=prfA)

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