Structure of PDB 5f1l Chain A

Receptor sequence
>5f1lA (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMK
DKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMM
SKERLLALKRSMS
3D structure
PDB5f1l Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5U2 A H42 F44 F45 F47 V49 I53 Y99 N100 Y106 H21 F23 F24 F26 V28 I32 Y78 N79 Y85 MOAD: ic50=21nM
PDBbind-CN: -logKd/Ki=7.68,IC50=21nM
BindingDB: IC50=21nM
External links
PDB RCSB:5f1l, PDBe:5f1l, PDBj:5f1l
PDBsum5f1l
PubMed26914985
UniProtQ9H8M2|BRD9_HUMAN Bromodomain-containing protein 9 (Gene Name=BRD9)

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