Structure of PDB 5ez5 Chain A

Receptor sequence
>5ez5A (length=168) Species: 9606 (Homo sapiens) [Search protein sequence]
YDYLFKVVLIGDVGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDG
KTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLK
ELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALD
STNVEAAFQTILTEIYRI
3D structure
PDB5ez5 Crystal structure of active Rab11A (S20V) in complex with GTP
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A S25 T43 S18 T36
BS02 GTP A V20 G21 G23 K24 S25 N26 F36 L38 S40 S42 T43 A68 N124 K125 D127 L128 S154 A155 L156 V13 G14 G16 K17 S18 N19 F29 L31 S33 S35 T36 A61 N117 K118 D120 L121 S147 A148 L149
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:5ez5, PDBe:5ez5, PDBj:5ez5
PDBsum5ez5
PubMed
UniProtP62491|RB11A_HUMAN Ras-related protein Rab-11A (Gene Name=RAB11A)

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