Structure of PDB 5ez0 Chain A

Receptor sequence
>5ez0A (length=90) Species: 9606 (Homo sapiens) [Search protein sequence]
PHDNLVLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRL
NEGDQVVLINGRDIAEHTHDQVVLFIKASCGELMLLVRPN
3D structure
PDB5ez0 Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma.
ChainA
Resolution2.35 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R527 F528 G529 F530 N531 V532 Q538 S545 H579 V583 I586 R17 F18 G19 F20 N21 V22 Q28 S35 H69 V73 I76
BS02 peptide A A548 P549 A38 P39
External links
PDB RCSB:5ez0, PDBe:5ez0, PDBj:5ez0
PDBsum5ez0
PubMed27246854
UniProtP29074|PTN4_HUMAN Tyrosine-protein phosphatase non-receptor type 4 (Gene Name=PTPN4)

[Back to BioLiP]