Structure of PDB 5eyz Chain A

Receptor sequence
>5eyzA (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
HDNLVLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLN
EGDQVVLINGRDIAEHTHDQVVLFIKASCERHSGELMLLVRPN
3D structure
PDB5eyz Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma.
ChainA
Resolution2.09 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R527 F528 G529 F530 N531 V532 K533 Q538 S545 H579 D580 V583 R16 F17 G18 F19 N20 V21 K22 Q27 S34 H68 D69 V72
External links
PDB RCSB:5eyz, PDBe:5eyz, PDBj:5eyz
PDBsum5eyz
PubMed27246854
UniProtP29074|PTN4_HUMAN Tyrosine-protein phosphatase non-receptor type 4 (Gene Name=PTPN4)

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