Structure of PDB 5exx Chain A

Receptor sequence
>5exxA (length=256) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
REPNLFRSLVGTSRAIQQVRQMMQQVADTDASVLILGESGTGKEVVARNL
HYHSKRREGPFVPVNCGAIPAELLESELFGHEKGAFTGAITSRAGRFELA
NGGTLFLDEIGDMPLPMQVKLLRVLQERTFERVGSNKTQNVDVRIIAATH
KNLEKMIEDGTFREDLYYRLNVFPIEMAPLRERVEDIALLLNELISRMEH
EKRGSIRFNSAAIMSLCRHDWPGNVRELANLVERLAIMHPYGVIGVGELP
KKFRHV
3D structure
PDB5exx Mechanistic insights into c-di-GMP-dependent control of the biofilm regulator FleQ from Pseudomonas aeruginosa.
ChainA
Resolution3.311 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C2E A R144 E330 S333 R334 H337 R7 E193 S196 R197 H200 PDBbind-CN: -logKd/Ki=5.39,Kd=4.1uM
BS02 C2E A L142 F143 R144 R185 N186 Y189 R334 L5 F6 R7 R48 N49 Y52 R197 PDBbind-CN: -logKd/Ki=5.39,Kd=4.1uM
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008134 transcription factor binding
GO:0016887 ATP hydrolysis activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5exx, PDBe:5exx, PDBj:5exx
PDBsum5exx
PubMed26712005
UniProtG3XCV0|FLEQ_PSEAE Transcriptional regulator FleQ (Gene Name=fleQ)

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