Structure of PDB 5ewh Chain A

Receptor sequence
>5ewhA (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
EMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFF
TMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGG
AVLRQARRQAEKM
3D structure
PDB5ewh Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
ChainA
Resolution1.63 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5SG A I652 N708 F714 I26 N82 F88 MOAD: Kd=170uM
PDBbind-CN: -logKd/Ki=3.77,Kd=170uM
BindingDB: Kd=170000nM
External links
PDB RCSB:5ewh, PDBe:5ewh, PDBj:5ewh
PDBsum5ewh
PubMed27167503
UniProtP55201|BRPF1_HUMAN Peregrin (Gene Name=BRPF1)

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