Structure of PDB 5eua Chain A

Receptor sequence
>5euaA (length=263) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
DFEHAISDLEAHNQAKIGVALVSENGNLIQGYRANERFAMCSTFKLPLAA
LVLSRIDAGEENPERKLHYDSAFLEEYAPAAKRYVATGYMTVTEAIQSAL
QLSDNAAANLLLKEVGGPPLLTKYFRSLGDKVSRLDRIEPTLNTNTPGDE
RDTTTPMSMAQTVSKLIFGDTLTYKSKGQLRRLLIGNQTGDKTIRAGLPD
SWVTGDKTGSCANGGRNDVAFFITTAGKKYVLSVYTNAPELQGEERALLI
ASVAKLARQYVVH
3D structure
PDB5eua Crystal Structure of the Pseudomonas aeruginosa BEL-1 Extended-Spectrum beta-Lactamase and Its Complexes with Moxalactam and Imipenem.
ChainA
Resolution1.85 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) S62 K65 S123 E159 K227 S230
Catalytic site (residue number reindexed from 1) S42 K45 S103 E139 K207 S210
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3P7 A S62 K65 Y97 S123 N125 N163 T228 G229 S230 C231 S42 K45 Y77 S103 N105 N143 T208 G209 S210 C211
Gene Ontology
Molecular Function
GO:0008800 beta-lactamase activity
GO:0016787 hydrolase activity
Biological Process
GO:0017001 antibiotic catabolic process
GO:0030655 beta-lactam antibiotic catabolic process
GO:0046677 response to antibiotic

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5eua, PDBe:5eua, PDBj:5eua
PDBsum5eua
PubMed27671060
UniProtQ3SAW3

[Back to BioLiP]