Structure of PDB 5eu1 Chain A

Receptor sequence
>5eu1A (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
STPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMK
DKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMM
SKERLLALKRSMS
3D structure
PDB5eu1 Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor.
ChainA
Resolution1.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5SW A F44 F45 V49 I53 A54 N100 Y106 F23 F24 V28 I32 A33 N79 Y85 MOAD: Kd=15.4nM
PDBbind-CN: -logKd/Ki=7.81,Kd=15.4nM
BindingDB: Kd=0.794328nM,IC50=19nM
External links
PDB RCSB:5eu1, PDBe:5eu1, PDBj:5eu1
PDBsum5eu1
PubMed26914985
UniProtQ9H8M2|BRD9_HUMAN Bromodomain-containing protein 9 (Gene Name=BRD9)

[Back to BioLiP]