Structure of PDB 5es8 Chain A

Receptor sequence
>5es8A (length=759) Species: 54914 (Brevibacillus parabrevis) [Search protein sequence]
MGRILFLTTFMSKGNKVVRYLESLHHEVVICQEKVHAQSANLQEIDWIVS
YAYGYILDKEIVSRFRGRIINLHPSLLPWNKGRDPVFWSVWDETPKGVTI
HLIDEHVDTGDILVQEEIAFADEDTLLDCYNKANQAIEELFIREWENIVH
GRIAPYRQTAGGTLHFKADRDFYKNLNMTTVRELLALKRLCAEPKRGEKP
IDKTFHQLFEQQVEMTPDHVAVVDRGQSLTYKQLNERANQLAHHLRGKGV
KPDDQVAIMLDKSLDMIVSILAVMKAGGAYVPIDPDYPGERIAYMLADSS
AAILLTNALHEEKANGACDIIDVHDPDSYSENTNNLPHVNRPDDLVYVMY
TSGSTGLAKGVMIEHHNLVNFCEWYRPYFGVTPADKALVYSSFSFDGSAL
DIFTHLLAGAALHIVPSERKYDLDALNDYCNQEGITISYLPTGAAEQFMQ
MDNQSFRVVITGGDVLKKIERNGTYKLYNGYGPTECTIMVTMFEVDKPYA
NIPIGKPIDRTRILILDEALALQPIGVAGELFIVGEGLGRGYLNRPELTA
EKFIVHPQTGERMYRTGDRARFLPDGNIEFLGRLDNLVKIRGYRIEPGEI
EPFLMNHPLIELTTVLAKEQADGRKYLVGYYVAPEEIPHGELREWLGNDL
PDYMIPTYFVHMKAFPLTANGKVDRRALPDVVAPTDELEQQLAQVWSHVL
GIPQMGIDDHFLERGGDSIKVMQLIHQLKNIGLSLRYDQLFTHPTIRQLK
RLLTEQAAA
3D structure
PDB5es8 Synthetic cycle of the initiation module of a formylating nonribosomal peptide synthetase.
ChainA
Resolution2.547 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H73 D108 T351 F371 T484 E485 K589 R594 K672
Catalytic site (residue number reindexed from 1) H73 D108 T351 F371 T484 E485 K589 R594 K672
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5S4 A F395 D396 G462 G463 R591 G592 Y593 S729 I730 M733 F395 D396 G462 G463 R591 G592 Y593 S718 I719 M722
Gene Ontology
Molecular Function
GO:0031177 phosphopantetheine binding
Biological Process
GO:0009058 biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5es8, PDBe:5es8, PDBj:5es8
PDBsum5es8
PubMed26762462
UniProtQ70LM7|LGRA_BREPA Linear gramicidin synthase subunit A (Gene Name=lgrA)

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