Structure of PDB 5er8 Chain A

Receptor sequence
>5er8A (length=294) Species: 1214568 (Diaporthe amygdali) [Search protein sequence]
EFKYSEVVEPSTYYTEGLCEGIDVRKSKFTTLEDRGAIRAHEDWNKHIGP
CREYRGTLGPRFSFISVAVPECIPERLEVISYANEFAFLHDDVTDGKKRI
QSQLFLEMLAIDPECAKTTMKSWARTRFVELAKYIPYRIMDVGEMFWFGL
VTFGLGLHIPDHELELCRELMANAWIAVGLQNDIWSWPKERDAATLHGKD
HVVNAIWVLMQEHQTDVDGAMQICRKLIVEYVAKYLEVIEATKNDESISL
DLRKYLDAMLYSISGNVVWSLECPRYNPDVSFNKTQLEWMRQGL
3D structure
PDB5er8 Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase.
ChainA
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) A69 F89 E194 W319
Catalytic site (residue number reindexed from 1) A68 F88 E144 W269
Enzyme Commision number 2.5.1.29: geranylgeranyl diphosphate synthase.
4.2.3.43: fusicocca-2,10(14)-diene synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D92 D96 D91 D95
BS02 MN A D92 D96 D91 D95
BS03 MN A R188 N232 S236 E240 R138 N182 S186 E190
BS04 NRD A D92 R188 N232 S236 K239 E240 R325 Y326 D91 R138 N182 S186 K189 E190 R275 Y276
External links
PDB RCSB:5er8, PDBe:5er8, PDBj:5er8
PDBsum5er8
PubMed26734760
UniProtA2PZA5|FC1_PHOAM Fusicoccadiene synthase (Gene Name=PaFS)

[Back to BioLiP]