Structure of PDB 5eps Chain A

Receptor sequence
>5epsA (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
EMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFF
TMKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGG
AVLRQARRQAEKM
3D structure
PDB5eps Twenty Crystal Structures of Bromodomain and PHD Finger Containing Protein 1 (BRPF1)/Ligand Complexes Reveal Conserved Binding Motifs and Rare Interactions.
ChainA
Resolution1.47 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5QX A V657 P658 E661 V662 Y707 N708 F714 V31 P32 E35 V36 Y81 N82 F88 MOAD: Kd=38uM
PDBbind-CN: -logKd/Ki=4.42,Kd=38uM
BindingDB: Kd=38000nM
External links
PDB RCSB:5eps, PDBe:5eps, PDBj:5eps
PDBsum5eps
PubMed27167503
UniProtP55201|BRPF1_HUMAN Peregrin (Gene Name=BRPF1)

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